Presentations
Abstracts, Posters and Presentations
P. Singh, P.R. Gajjala, H.H. Ediga, C.P. Vemulapalli, V. Sontake, S. Shambhu, M. Sharma, A.G. Jegga, H. Miyazaki, S.K. Huang, M. Walters, and S.K. Madala. 2023. Dysregulated Sox9 Overexpression in Multiple Lung Cells Contributes to Severe Fibrotic Lung Disease. A65. THE ALVEOLAR NICHE IN THE SPOTLIGHT OF LUNG FIBROSIS. May 1, 2023, A2189-A2189.
Ananthamohan K, Baby A, Jegga A, Sadayappan S. Abstract P3038: Novel MicroRNAs Targeting Myosin Binding Protein-C3 Gene In Hypertrophic Cardiomyopathy. Circulation Research. 2023;133(Suppl_1):AP3038-AP3038. doi:doi:10.1161/res.133.suppl_1.P3038.
Nguyen V, Gao C, Hochman ML, Friedman, H.I., Chen, E.H., Wang, Y., Jegga, A., Nelson, J.S., and Tan, W. (2023). Abstract 14173: Generation and Characterization of Clinically Relevant Disease Models for Port Wine Birthmark Using Induced Pluripotent Stem Cells. Circulation. 2023;148(Suppl_1):A14173-A14173. doi:doi:10.1161/circ.148.suppl_1.14173
M. Sarangdhar, V. Kolli, J. Gomez-Arroyo, M. Gu, J.M. Elwing, and A. Jegga. 2023. Predicting Real-world Modifiers for Drugs Inducing Pulmonary Arterial Hypertension. A71. MATTERS OF THE HEART AND LUNGS: STUDIES ON CARDIOPULMONARY VASCULAR DISEASE. May 1, 2023, A2362-A2362.
Dhaliwal J, Liu X, Reigle J, Sharma M, Lopez-Nunez O, Walters T, Collins M, Hyams J, Siddiqui I, Denson L, Jegga AG, Prasath S. 2023. Development of an optimal machine learning model using treatment naïve diagnostic pathology images to predict steroid-free clinical remission at one year in pediatric ulcerative colitis. Inflammatory Bowel Diseases, 29 (Supplement_1): S56–S57, https://doi.org/10.1093/ibd/izac247.109
Jegga AG. 2022. Pharmacogenomics and Bioinformatics in Drug Discovery. Principles of Pediatric Clinical Pharmacology and Therapeutics Course. Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) National Institutes of Health (NIH) November 30, 2022.
Jegga AG. 2022. Mining Bio-Medical Mountains: How Data Science can help Biomedical Research and Health Sciences. High School Speaker Outreach, SciNHS Mason High School Science National Honor Society, Mason High School, Cincinnati, December 8, 2022.
Jegga A 2022. Secondary Analysis of Data to Enable Translational Research. University of South Carolina School of Medicine Columbia Seminar, November 21, 2022.
Jegga A 2022. Data-driven approaches to support translational research in respiratory medicine. Univeristy of vermont, Vermont Lung Center Seminar, March 15, 2022.
Cheng-Yu Tsai, Toshie Saito, Mayur Sarangdhar, Maisam Abu-El-Haija, Li Wen, Bomi Lee, Murli Manohar, Monique T. Barakat, Kévin Contrepois, Na Bo, Ying Ding, Kristen E. Stevenson, Elena Ladas, Lewis B. Silverman, Loredana Quadro, Tracy G. Anthony, Anil Goud Jegga, and Sohail Z. Husain. 2022. Vitamin A and association with asparaginase-associated pancreatitis in children with acute lymphocytic leukemia. Journal of Clinical Oncology 2022 40:16_suppl, 10021-10021
Jurickova I, Huron A, Angerman E, Bonkowski E, Jegga A, Haberman Y, Denson L 2022. Eicosatetraynoic acid regulates mitochondrial and extra-cellular matrix gene expression and tissue stiffness in a human intestinal organoid model of ileal crohn’s disease. Inflammatory Bowel Diseases, Volume 28, Issue Supplement_1, February 2022, Pages S62–S63, DOI: 10.1093/ibd/izac015.100
Y Haberman Ziv, T Braun, K Sosnovski, A Amir, K VanDussen, I U Igor Ulitsky, A Griffiths, T Walters, D Mack, B Boyle, S Kugathasan, Jegga A, J Hyams, L Denson PROTECT cohort. 2022. Long ncrna landscape in the rectum of treatment naïve early onset ulcerative colitis highlights association with severity and early and late disease outcome, with potential role in epithelial metabolic functions. Journal of Crohn's and Colitis, Volume 16, Issue Supplement_1, January 2022, Pages i187–i189, DOI:10.1093/ecco-jcc/jjab232.218
Desai, D. A., Rao, V., Jegga, A., Dhandapany, P., & Sadayappan, S. 2021. Abstract MP264: Heterogeneous Distribution Of Mutations In Myosin Binding Protein-c Paralogs. Circulation Research, 129(Suppl_1). doi:10.1161/res.129.suppl_1.mp264
Jegga AG 2021. Secondary Analyses of Existing Data Sets to Decipher Drug-Induced Pancreatitis. American Pancreatic Association 2021 Annual Meeting. November 3-6, 2021, Eden Roc Miami Beach, USA.
Cheng-Yu Tsai, Toshie Saito, Mayur Sarangdhar, Maisam Abu-El-Haija, Loredana Quadro, Tracy G. Anthony, Anil Jegga, Sohail Z. Husain. 2021. A Multi-Systems Approach with Big Data from Adverse Event Reporting and Health Records, Clinical Biospecimens, and Experimental Animal Data Reveal That Retinoids Impact Asparaginase-Associated Pancreatitis Outcomes in Leukemic Patients. Gastroenterology, Volume 161, Issue 2, e24 - e25.
Phillip P. Minar, Anil Jegga, Sudhir Ghandikota, Rebekah Karns, Jeffrey S. Hyams, Joshua D. Noe, Brendan M. Boyle, Michael J. Rosen, Lee A. Denson 2021. PLASMA PROTEOMIC RESPONSE SIGNATURE FOR CHILDREN RECEIVING INFLIXIMAB FOR CROHN'S DISEASE. Gastroenterology, Volume 160, Issue 6, S-145 - S-146.
Yael Haberman, Najeeha T. Iqbal, Sudhir Ghandikota, Indika Mallawaarachchi, Tzipi Braun, Phillip J. Dexheimer, Najeeb U. Rehman, Rotem Hadar, Kamran Sadiq, Zubair Ahmad, Romana Idrees, Junaid Iqbal, Sheraz Ahmed, Aneeta Hotwani, Fayaz A. Umrani, Lubaina Ehsan, Greg Medlock, Sana Syed, Christopher A. Moskaluk, Jennie Z. Ma, Anil Jegga, Sean Moore, Asad Ali, Lee A. Denson 2021. IMMUNE AND METABOLIC PATHOGENESIS OF ENVIRONMENTAL ENTERIC DYSFUNCTION IN CHILDHOOD UNDERNUTRITION: A BIRTH INCEPTION COHORT. Gastroenterology, Volume 160, Issue 6, S-615.
P Gajjala, D Soundararajan, RK Kasam, D Sinner, SK Huang, A Jegga, SK Madala. 2021. SOX9 Is a Positive Regulator of Fibroblast Activation in Idiopathic Pulmonary Fibrosis. ATS 2021 International Comference. Am J Respir Crit Care Med 2021;203:A4406
Jegga AG. 2020. Pharmacogenomics and Bioinformatics in Drug Discovery. Principles of Pediatric Clinical Pharmacology Course. Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) National Institutes of Health (NIH) October 28, 2020. Presentation.
P Gajjala, RK Kasam, D Soundararajan, D Sinner, N Gupta, A Jegga, SK Madala. 2020. Aberrant Upregulation of SOX9 by Distal Lung Mesenchymal Cells in the Pathogenesis of Idiopathic Pulmonary Fibrosis. D27. CELLULAR RESPONSES INFORMING LUNG REPAIR, A6386-A6386. ATS 2020 International Comference.
RK Kasam, S Ghandikota, GB Reddy, SK Huang, A Jegga, SK Madala 2020. Wilms' Tumor 1 Induces Aurora Kinase B Expression to Augment Fibroblast Activation in Pulmonary Fibrosis. A63. MEDIATORS OF LUNG FIBROSIS, A2267-A2267. ATS 2020 International Comference.
DJK Yombo, B Singh, N Gupta, A Jegga, SK Madala. 2020. The Loss of Interleukin 31 Receptor Alpha (IL-31RA)-Driven Signaling Attenuates Lung Function Decline in Pulmonary Fibrosis. B34. ILD CELLULAR MECHANISMS, A3076-A3076. ATS 2020 International Comference.
S Ghandikota, SK Madala, A Jegga 2020. An Information-Theoretic Approach to Identify and Infer Gene Regulatory Networks in Idiopathic Pulmonary Fibrosis. B64. MECHANISTIC ADVANCES IN LUNG FIBROSIS, A4026-A4026. ATS 2020 International Comference.
Haberman Y, Minar PP, Karns R, Dexheimer PJ, Ghandikota S, Tegge S, Shapiro D, Shuler B, Venkateswaran S, Braun T, Walters TD, Baldassano RN, Noe JD, Kellermayer R, Markowitz J, Dotson JL, Mack DR, Griffiths AM, Heyman MB, Baker SS, Moulton DE, Patel AS, Gulati AD, Steiner SJ, Leleiko NS, Otley A, Oliva-Hemker M, Ziring D, Gokhale RR, Kim SC, Guthery S, Cohen SA, Snapper SB, Aronow BJ, Stephens MC, Gibson G, Dubinsky MC, Hyams JS, Kugathasan S, Jegga AG, Denson LA. 2020. Pre-treatment mucosal inflammatory and wound healing gene programs reveal mechanisms associated with future stricturing behavior during five year follow-up in pediatric crohn's disease. Gastroenterology 158 (6), S-187-S-188. DOI:https://doi.org/10.1016/S0016-5085(20)31152-5
Y Huang, K Arora, KS Mun, F Yang, S Yarlagadda, A Jegga, TE Weaver, Naren AP. 2020. ER luminal erad as a novel target to rescue mutant cftr in the intestine. Gastroenterology 158 (6), S-125. DOI:https://doi.org/10.1016/S0016-5085(20)30992-6
Jegga AG. 2019. Pharmacogenomics and Bioinformatics in Drug Discovery. Principles of Pediatric Clinical Pharmacology Course. Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) National Institutes of Health (NIH) November 20, 2019.
Jegga AG, 2019. Data repurposing for drug repositioning. - The 8th Annual Drug Repositioning and Repurposing Conference, Washington, DC - September 23-24, 2019.
Jegga AG, 2019. Secondary analysis of data to enable translational research. University of Hyderabad, Hyderabad, India - August 1, 2019.
Jegga AG, 2019. Secondary analysis of data to enable translational research. Center for Computational Engineering and Networking (CEN), Amrita Vishwa Vidyapeetham, Coimbatore, Tamil Nadu, India - July 25, 2019.
RK Kasam, BR Geereddy, V Sontake, A Jegga, SK Madala, 2019. Aurora Kinase B Is a Positive Regulator of Proliferation and Survival of Lung-Resident Fibroblasts in Severe Fibrotic Lung Disease. C58. MECHANISMS OF PULMONARY FIBROSIS, A5253-A5253. American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX.
D Soundararajan, SK Madala, A Jegga 2019. Repurposing an Opioid Receptor Antagonist as a Treatment for Idiopathic Pulmonary Fibrosis. A29. EMERGING CONCEPTS IN LUNG FIBROSIS, A1228-A1228. American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX.
V Sontake, D Soundararajan, JR Arron, A Jegga, SK Madala. 2019. Pirfenidone Therapy Attenuates Lung Function Decline in a Mouse Model of TGFα-Induced Pulmonary Fibrosis. C64. PULMONARY FIBROSIS MODELS AND MECHANISTIC INSIGHTS, A5414-A5414. American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX.
S Ghandikota, SK Madala, A Jegga. 2019. Unsupervised and Supervised Analysis to Identify Novel Candidate Genes and Therapeutics for Idiopathic Pulmonary Fibrosis. D29. LUNG MULTI-OMICS TO MECHANISM, A6074-A6074. American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX.
S Ghandikota, M Lape, A Jegga. 2019. Multi-Transcriptome-Based Network Analysis to Identify Novel Genes and Candidate Small Molecules for Pulmonary Arterial Hypertension. C60. VASCULAR BIOLOGY IN LUNG DISEASE, A5300-A5300. American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX
Yella J and Jegga AG. 2019. Heterogeneous drug network modules to predict and characterize drug-drug interactions. AMIA 2019 Informatics Summit, March 25-28, San Francisco, USA.
Yaddanapudi S and Jegga AG 2019. Discovering drug-disease interactions through phenotype-based drug modules. AMIA 2019 Informatics Summit, March 25-28, San Francisco, USA.
Jegga AG. 2018. Pharmacogenomics and Bioinformatics in Drug Discovery. Principles of Pediatric Clinical Pharmacology Course. Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) National Institutes of Health (NIH) October 24, 2018. Presentation.
Treble-Barna A, Jegga A, Kurowski B, Taylor HG, Yeates K, Martin L, Wade S, Pilpenko V. 2018. Genetic Influences On Behavioral Outcomes After Childhood TBI: A Novel System Biology-Informed Approach. Archives of Physical Medicine and Rehabilitation 99(11): e137-e138.
V Sontake, R Kasam, V Odayar, SH Randell, JP Clancy, AG Jegga, S Madala 2018. Fibrocytes accumulate in the lungs of cystic fibrosis. Pediatric Pulmonology 53: 193-193.
Kurowski B, Treble-Barna A, Pilpenko V, Martin L, Wade S, Yeates K, Taylor GH, Jegga AG. 2018. Genetic influences on behavioral outcomes after childhood tbi: a novel system biology-informed approach. 4th Federal Interagency Conference on Traumatic Brain Injury. Washington DC, USA. June 11-13, 2018.
Y. Wang, S. Yaddanapudi, J. Yella, V. Sontake, S.K. Madala, A. Jegga. 2018. Integrative Omics to Discover Drug Repurposing Candidates for Idiopathic Pulmonary Fibrosis. ATS Conference 2018, May 18-23, San Diego, USA
Y. Wang, J. Yella, S.K. Madala, A. Jegga. 2018. Prioritizing Idiopathic Pulmonary Fibrosis Candidate Genes Based on "Guilt by Association" Analysis. ATS Conference 2018, May 18-23, San Diego, USA
M. Sarangdhar, P.B. Nagaraja, A. Jegga. 2018. Joint Analysis of Biomedical and Genomic Data to Characterize Drug-Induced Pulmonary Arterial Hypertension. ATS Conference 2018, May 18-23, San Diego, USA
R.K. Kasam, G.B. Reddy, A.G. Jegga, S.K. Madala. 2018. Molecular Regulation of Survival Pathways in Multiple Mesenchymal Cells. ATS Conference 2018, May 18-23, San Diego, USA
V. Sontake, R.K. Kasam, B.R. Geereddy, D. Sinner, E.S. White, A. Jegga, S.K. Madala. 2018. Wilms’ Tumor 1 Is a Positive Regulator of Fibroblast Activation in Severe Fibrotic Lung Disease. ATS Conference 2018, May 18-23, San Diego, USA
X. Li, S.S. Wong, J. Zhao, A. Jegga, K. Shayan, J.S. Hagood. 2018. Abnormal Surfactant Protein Expression and Activation of Anti-Apoptotic Pathways in Severe Interstitial Lung Disease (ILD) in Rubinstein-Taybi Syndrome (RTS). ATS Conference 2018, May 18-23, San Diego, USA
Jegga AG. Data-driven approaches to identify candidate therapeutics for rare lung disorders. World Orphan Drug Congress USA 2018; 25-27 April, 2018, Maryland.
Kronk C and Jegga AG. GNOMICS: A one-stop shop for biomedical and genomic data. AMIA 2018 Informatics Summit, March 12 - 15, San Francisco, USA.
Jiang A and Jegga AG 2018. Characterizing drug-related adverse events by joint snalysis of biomedical and genomic data: A case study of drug-induced pulmonary fibrosis. AMIA 2018 Informatics Summit, March 12 - 15, San Francisco, USA.
Wang Y, Arora K, Yang F, Chen J, Naren AP, Jegga AG. 2017. Harnessing small molecule big data and intestinal organoid-based functional screening for cystic fibrosis drug discovery. The 31st Annual North American Cystic Fibrosis Conference, Indiana Convention Center, Indianapolis, Indiana, November 2–4, 2017. Pediatric Pulmonology 52: S299-S300.
Sarangdhar M, Aronow B, Jegga AG, Turpin B, Breese EH, Perentesis JP. 2017. Large scale adverse event data mining for targeted therapies development. 2017 ASCO Annual Meeting. J Clin Oncol 35, 2017 (suppl; abstr 2538).
Sontake V, Wang Y, Kasam RK, Reddy GB, White ES, Jegga AG, Madala SK. 2017. Therapeutic inhibition of Hsp90 attenuates fibroblast activation involved in severe fibrotic lung disease. ATS Conferences, C76. HEAT SHOCK PROTEIN. Am J Repir Crit Care Med: 195: A6379.
Smith EA, Gole B, Willis NA, Eric KF, Jegga AG, Ali AM, Guo H, Meetei AR, Andreassen PR, Kappes F, Scully R, Wiesmüller L and Susanne WI. 2017. DEK is critical for homologous recombination and its loss is synthetic lethal with DNA-PK inhibition. Molecular Cancer Research 15 (4 Supplement): PR21-PR21. DOI: 10.1158/1557-3125.DNAREPAIR16-PR21.
Jegga AG. 2016. Translational bioinformatics: Integrative omics-based approach to human disease. August 10, 2016. National Institute of Nutrition, India.
Vemuri B, Wang Y, Chen J, Jegga AG. 2016. Integrative omics to discover candidate therapeutics for glioblastoma. August 5, 2016. University of Cincinnati, Cincinnati, USA.
Jegga AG. 2016. The needles ARE in the haystack! Integrated omics data-driven approaches and translational medicine. May 24, 2016. University of Pittsburgh, Pittsburgh, USA.
Jegga AG. 2016. Systems biology approaches for drug repositioning in cystic fibrosis. Cystic Fibrosis Data Conference. Jan 6, 2016. Cincinnati Children's Hospital Medical Center, Cincinnati, USA.
Jegga AG. 2015. Computational screening & drug repurposing for CF. Cystic Fibrosis -Research Development Program (CF-RDP), CF External Advisory Committee meeting. November 8-9, 2015, Cincinnati Children's Hospital Medical Center, Cincinnati, USA.
Malek E, Karns R, Jegga AG, Jagannathan S, Vad N, Malek MAY, Driscoll JJ. 2015. Long non-coding RNAs deregulated in Multiple Myeloma impact therapeutic response to proteasome inhibitors. In: Proceedings of the 106th Annual Meeting of the American Association for Cancer Research; 2015 Apr 18-22; Philadelphia, PA. Philadelphia (PA): AACR; Cancer Res 2015;75(15 Suppl):Abstract nr 153. doi:10.1158/1538-7445.AM2015-153
Jegga AG 2015. Computational drug repositioning candidate discovery: Heterogeneous data integration & mining. Opportunities and challenges in combination therapy for Alzheimer's disease advisory panel. Keep Memory Alive Event Center, Cleveland Clinic Lou Ruvo Center for Brain Health Campus, Las Vegas.
Aronow BJ, Wang Y, Jegga AG, Perl AKT,Brunskill E, Potter S, Kitzmiller J, Xu Y, Whitsett JA. 2015. Implicating a multi-cellular interactome responsible for integrative regulation of cell-specific differentiation, branching morphogenesis, vascularization, and organ-scale patterning during the saccular phase of lung development. Am J Respir Crit Care Med. 191: A5129.
Jegga AG. 2015. Network Medicine: Systems biology based approach to human disease. C R Rao AIMSCS. University of Hyderabad, Hyderabad, India. Feb. 10, 2015. Presentation.
Malek E, Latif T, Jegga AG, Jagannathan S, Vad N, Malek MAY, Driscoll JJ. 2014. Correlation of Non-Coding RNA Expression with Response to Proteasome Inhibitors in Multiple Myeloma. Blood, 124 (21): 3415-3415.
Velu CS, Cahubey A, Phelan JD, Horman SR, Wunderlich M, Guzman ML, Jegga AG, Zeleznik-Le NJ, Chen J, Mulloy JC, Cancelas JA, Jordan CT, Aronow BJ, Marcuccu G, Bhat B, Gebelein B, Grimes HL. microRNA-mediated leukemia-initiating cell activity. In: Proceedings of the 105th Annual Meeting of the American Association for Cancer Research; 2014 Apr 5-9; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 74(19 Suppl): Abstract nr 979. doi:10.1158/1538-7445.AM2014-979.
Jegga AG 2014. Disease Gene Ranking - Tutorial - Great Lakes Bioinformatics (GLBIO) Conference May 16-18, 2014, Cincinnati, USA. Presentation.
Wu C, Bardes E, Jegga AG and Aronow BJ 2014. ToppMiR: Significance-ranking of microRNAs and their mRNA Targets Based on Biological Context and Functional Associations. Great Lakes Bioinformatics (GLBIO) Conference May 16-18, 2014, Cincinnati, USA.
Schriner A, Sarangdhar M, Jegga AG and Aronow BJ 2014. Crowdsourcing Innovation to Boost Pathway Discovery from Literature Great Lakes Bioinformatics (GLBIO) Conference May 16-18, 2014, Cincinnati, USA.
Sarangdhar M, Tabar S, Kushwaha A, Jegga AG and Aronow BJ 2014. AERSMine: A High-resolution Multiple Cohort Analyzer Based on the FDA’s Adverse Events Reporting System Data. Great Lakes Bioinformatics (GLBIO) Conference May 16-18, 2014, Cincinnati, USA.
Hankey W, McIlhatton MA, Lan X, Jegga AG, Jin VX, Aronow BJ, Groden J. 2013. Direct transcriptional functions of the APC tumor suppressor in regulating gene expression. In: Proceedings of the Third AACR International Conference on Frontiers in Basic Cancer Research; Sep 18-22, 2013; National Harbor, MD. Philadelphia (PA): AACR; Cancer Res 2013;73(19 Suppl):Abstract nr A21.
Jegga AG, Wittenberg G, Yao X, Yieh L, Chen G, Narayan V 2013. An integrated -omics approach to understanding psychoneuroimmunology crosstalk. ACNP (American College of Neuropsychopharmacology) 52nd Annual Meeting, December 8-12, 2013, Florida, USA. Neuropsychopharmacology 38: S108–S272.
Wu C, Bakshi A, Aronow B, Jegga AG, and Bhatnagar R. 2013. A Biclustering Algorithm to Discover Functional Modules from ENCODE ChIP-seq Data. IEEE International Conference on Data Mining Workshops (ICDMW 2013), 7-10 December, Dallas, Texas.
Jegga AG. 2013. Knowledge-mining and repurposing strategies for orphan disease target discovery. Presented at Genzyme, Boston, November 12, 2013 (Invited talk).
Wu C, Gudivada RC, Aronow BJ, Jegga AG. 2013. Computational drug repositioning through heterogeneous network clustering. Presented at International Conference on Intelligent Biology and Medicine (ICIBM 2013). August 11-13, 2013, Nashville, TN, USA.
Sarangdhar M, Kushwaha A, Jegga AG, Aronow BJ. 2013. AERSmine: A phenome-pharmacome web datamine based on the FDA’s adverse events reporting system data. AMIA Summit on Translational Bioinformatics, March 18-20, 2013, San Francisco, CA, USA.
Zhu C, Jegga AG 2012. Integrated heterogeneous network analyses to identify drug repositioning candidates for orphan diseases. Presented at International Conference on Intelligent Biology and Medicine (ICIBM 2012). April 22-24, 2012, Nashville, TN, USA.
Bessho K, Mourya R, Dilbone E, Kaimal V, Xu H, Shivakumar P, Rao M, Jegga AG and Bezerra JA. 2011. A molecular signature of biliary atresia highly distinct from other cholestatic diseases at diagnosis. Presented at American Association for the Study of Liver Diseases (AASLD) 62nd Annual Meeting, San Francisco, CA: November 4-8, 2011. Hepatology 54 (Supplement 1): 421A-421A.
Bessho K, Mourya R, Sheridan R, Kaimal V, Xu H, Mohanty SK, Shivakumar P, Jegga AG and Bezerra JA. 2011. Screening and identification of potential micrornas involved in bile duct injury in experimental biliary atresia. Presented at American Association for the Study of Liver Diseases (AASLD) 62nd Annual Meeting, San Francisco, CA: November 4-8, 2011. Hepatology 54 (Supplement 1): 697A-697A.
Zdenek A. Kaimal V, Stambrook P, Jegga AG. 2010. MicroRNA-mediated gene regulation of CDC25A: Impact of Carcinogenic environmental pollutants. CEG Pilot Project Symposium, University of Cincinnati, OH. May 26, 2010.
Alqadah F, Bhatnagar R, Jegga AG. 2010. Mining Maximally Banded Matrices in Binary Data. SDM 2010: Tenth SIAM International Conference on Data Mining, Columbus, Ohio. April 29-May 1, 2010. (Selected as one of the 12 best papers accepted at SDM 2010).Abstract Download.
Deshmukh M, Bhatnagar R, Jegga AG. 2010. Simultaneous Search in Multiple Lattices for Knowledge Discovery. ISAIM 2010 (The Eleventh International Symposium on Artificial Intelligence and Mathematics), Fort Lauderdale, Florida January 6-8, 2010.
Jegga AG 2009. Integrative Functional Genomics. Department of Biomedical Engineering, University of Cincinnati, November 5, 2009.Presentation (BME Survey - 20 BME 601 - Autumn Quarter 2009).
Jegga AG 2009. Developing a knowledgebase project for disease research. Systems Biology & Physiology Third Annual Retreat, Genome Research Institute, University of Cincinnati, May 8, 2009.
Chaubey A, Horman SR, Velu CS, Bourdeau T, Zhu J, Paul W,, Jegga AG, Gebelein B, and Grimes HL. GFI1 Is a Tumor Suppressor in Myeloid Progenitors. 50th ASH Annual Meeting and Exposition. Dec 6-9, 2008.
Jegga AG 2008. Integrative Genomics For Understanding Disease Process - Mining Bio-Medical Mountains. Department of Biomedical Engineering, University of Cincinnati, November 6, 2008. Presentation (BME Survey - 20 BME 601 - Autumn Quarter 2008).
Jegga AG 2008. Making sense out of transcriptome - Integrative bioinformatic approaches. 3 S Biology Summer School. Trento, Italy, 18-22 August, 2008.The Centre for Integrative Biology (CIBIO), University of Trento, Italy Presentation; Hand-out (pdf).
Jegga AG 2008. Translational Genomics and Biomedical Ontologies. 3 S Biology Summer School. Trento, Italy, 18-22 August, 2008.The Centre for Integrative Biology (CIBIO), University of Trento, Italy Presentation.
Jegga AG 2008. Mining Bio-Medical Mountains - How Computer Science can help Biomedical Research and Health Sciences. Department of Computer Sciences, University of Cincinnati, June 23, 2008. Presentation
Jegga AG 2008. Mining Bio-Medical Mountains - How Computer Science can help Biomedical Research and Health Sciences. Department of Computer Sciences, University of Cincinnati, February 13, 2008. Presentation
Sinha AU, Phatak M, Bhatnagar R and Jegga AG 2007. Identifying functional binding motifs of tumor protein p53 using support vector machines. In Proceedings of International Conference on Machine Learning and Applications (ICMLA): 13-15 December 2007, Cincinnati, USA.
Jegga AG 2007. Systems biology based integrative approaches to identify and prioritize novel disease candidate genes. First virtual conference on "Bioinformatics to Systems Biology", November 16, 2007 (online at the Bioinformatics Organization) - Jointly organized by Bioinformatics.Org and the ISCB Regional Student Group, Denmark.Presentation
Kamath M, Houston I, Janovski A, Zhu X, Gowrisankar S, Jegga AG, and DeKoter R 2007. Myeloid Gene Activation and T Cell/Natural Killer Cell Gene Repression in Cells Expressing Two Distinct PU.1 Concentrations. Blood (ASH Annual Meeting Abstracts), Nov 2007; 110: Abstract 1242.
Horman SR, Chinamenveni S. Velu, Tristan Bourdeau, Avinash Baktula, Jinfang Zhu, William Paul, Jegga AG, Michael A. Caliguiri, Brian Gebelein, and H. Leighton Grimes A Conserved Mechanism of Transcription Factor Competition Controls Hematopoietic Progenitor Self-Renewal. Blood (ASH Annual Meeting Abstracts), Nov 2007; 110: Abstract 91.
Qu AX, Gudivada CR, Jegga AG, Neumann EK, Aronow BJ 2007. Semantic web-based data representation and reasoning applied to disease mechanism and pharmacology, 2nd International Workshop on Data Mining in Bioinformatics (DMB 2007).
Shaik SB, Jegga AG, Menon AG, and Pauletti GM 2007. Identification of novel peptide ligands for putative transcytosis receptors expressed in the human placenta. 2007 AAPS Annual Meeting and Exposition November 9-15, 2007. San Diego Convention Center San Diego, California.
Sinha AU*, Bhatnagar R and Jegga AG. 2007. Microregulation of a master regulatory network. Ohio Collaborative Conference on Bioinformatics (OCCBIO), Miami University, Oxford, Ohio, July 9-11. (*Awarded first prize for best student presentation)
Kaimal V*, Jegga AG and Aronow BJ. 2007 Predicting the functional impact of microRNAs on developmental processes. Ohio Collaborative Conference on Bioinformatics (OCCBIO), Miami University, Oxford, Ohio, July 9-11. (*Awarded third prize for best student presentation)
Gowrisankar S, Aronow BJ and Jegga AG. 2007. Transcriptional Genomics of Heart Development. Ohio Collaborative Conference on Bioinformatics (OCCBIO), Miami University, Oxford, Ohio, July 9-11.
Chen J, Huan X, Aronow BJ and Jegga AG. 2007. Improved human disease candidate gene prioritization using mouse phenotype. Ohio Collaborative Conference on Bioinformatics (OCCBIO), Miami University, Oxford, Ohio, July 9-11.
Gudivada RC, Qu AX, Jegga AG, Neumann EK, Aronow BJ. 2007. A Genome - Phenome Integrated Approach for Mining Disease-Causal Genes using Semantic Web. HCLS Workshop, 16th International World Wide Web Conference, May 8-12, 2007, Banff, Alberta, Canada.
Jegga AG, 2006. Systems biology-based Approaches to Identify Alzheimer's Disease-Susceptibility Genes. October 19, 2006, Hosted by Society for Neurochemistry (SNCI) & M.Tech. Bioinformatics Program, School of Life Sciences, University of Hyderabad, Hyderabad, India. Presentation; Abstract.
Velu CS, Jegga AG, Kaimal V, Aronow BJ Grimes HL 2006. miR-21 Is a Transcriptional Target of Growth Factor Independent -1; Implications for Transcriptional Regulation of microRNA. Blood (ASH Annual Meeting Abstracts) 2006 108: Abstract 1178
Ranga Chandra Gudivada, Qu X, Jegga AG, Neumann EK, Aronow BJ. 2006. Relevance-Ranking and Inferencing of Disease Phenotype, Etiology, Pathophysiological Mechanism, and Therapeutic Opportunities Using Biomedical Semantic Web Methodologies. November 6, 2006, Workshop for W3C Semantic Web Health Care and Life Sciences, Georgia Center, Athens, GA Abstract.
Jegga AG, Gowrisankar S, Sychay G, Chen J, Gudivada RC, Kong S, Deshmukh MA, Muthukrishnan A and Aronow BJ 2005. Systems Biology Approaches to Integrative Biomedical Informatics. Genotype-To-Phenotype Correlation in Health and Disease, Welches, Oregon December 4-8. Hosted by The Center for Research on Occupational and Environmental Toxicology at Oregon Health and Science University. Poster; Abstract.
Chen J, Jegga AG and Aronow BJ 2005. UMLS Concept Indexing of OMIM Clinical Synopsis and Knowledge Extraction. 13th Annual International Conference of Intelligent Systems for Molecular Biology (ISMB) 2005 Detroit, Michigan, June 25-29.
Gowrisankar S, Chen J, Jegga AG and Aronow BJ 2005. Integrative bioinformatic approaches for functional analysis of non-synonymous single nucleotide polymorphisms. 13th Annual International Conference of Intelligent Systems for Molecular Biology (ISMB) 2005 Detroit, Michigan, June 25-29.
Gudivada RC, Jegga AG and Aronow BJ 2005. Analysis of metastasis suppressor genes: comparative genomics and systems biology approaches. 13th Annual International Conference of Intelligent Systems for Molecular Biology (ISMB) 2005 Detroit, Michigan, June 25-29.
Inga A*, Menendez D*, Jegga AG*, Aronow BJ and Resnick MA 2005. Evolutionary separation of the p53 regulatory network between mice and humans based on response element rules and pattern search. American Association of Cancer Research (AACR) 96th Annual Meeting, April 16-20, 2005, Anaheim/Orange County, CA, USA (* equal contribution).
Gowrisankar S, Gudivada RC, Chen J, Kong S, Gupta A, Deshmukh A, Deshmukh M, Jegga AG and Aronow BJ. Systems Biology-based Bioinformatics Approaches to the Analysis of Genes and Diseases of the Digestive System: GenomeTrafac, Cismols, Polydoms, and Abstrainer. Digestive Disorder Research and Development Center (DDRDC) Scientific Retreat and External Advisory Board Meeting, Cincinnati Children's Hospital Medical Center (CCHMC), Cincinnati, Jan 22, 2005.
Chen J, Gowrisankar S, Gudivada RC, Jegga AG, Aronow BJ. Integrative Bioinformatics Approaches for Studying the Impact of Genomics and Understanding the Disease Processes. University of Cincinnati Graduate Poster Forum, Cincinnati, March 2005.
Jegga AG and Chen J 2004. Detection and visualization of conserved cis-element structures and their annotation using NLP-based extraction and GFF3-formatting of biomedical literature-derived SO features. Sequence Ontology Meeting August 19-20. University of California, Berkeley [Pdf].
Gu Y, Alvares CJ, Jasti AC, Jansen M, Bean J, Jegga AG, Aronow BJ, Williams DA 2004. Alteration of RhoH Expression Is Associated with Human Diffuse Large B-Cell Lymphoma. 46th ASH Annual meeting and exposition 2004. Blood November 16; 104 (11): ASH Meeting Abstracts.
Takemoto CM, Shahlaee AH, Ye Y, Zeller KI, Zablocki D, Huynh J, Huang S, DeKoter RP, Jegga AG, Aronow BJ, Dang CV, McDevitt MA. 2004. Transcriptional Regulation of a Distinct GATA-1 Isoform during Selection of the Mast and Erythroid Lineages. 46th ASH Annual meeting and exposition 2004. Blood November 16; 104 (11): ASH Meeting Abstracts.
Logan MA, Callahan E, Steele M, Jegga AG, Aronow BJ and Vetter ML 2004. Identification of shared proneural bHLH transcriptional targets. FASEB Summer Conference: Transcriptional Regulation During Cell Growth, Differentiation, and Development August 14-19, 2004, Saxtons River, Vermont.
Jegga AG 2003. Identification of compositionally similar cis-element clusters in coordinately regulated genes. Poster Presentation at Systems Biology: Genomic Approaches to Transcription Regulation Mar 6-9, Cold Spring Harbor Laboratory, New York. Poster;Abstract.
Jegga AG 2001 Comparative genomics approaches to the analysis of conserved cis-regulatory element clusters. Poster Presentation at 11th International Workshop BITS: Functional Expression and Evolutionary Analysis Nov 9-12, DOE, Virginia
Jegga AG, Gowrisankar S, Chen J, Adamczak R, Gupta A, Ramirez MA, Andra KSC, Carman JW and Aronow BJ. Cincinnati Comparative Mouse Genomics Centers Consortium: Bioinformatics Analysis Tools for Assessment of Human Gene Polymorphisms. Genes, Environment and Disease. Second annual CMGCC symposium, Environmental Genome Project, NIEHS, Boston, June 7 - 9, 2003Poster; Abstract.
Gowrisankar S, Deshmukh AS, Jegga AG and Aronow BJ 2004. An Integrative Approach for the Study of Sequence Variation Impact on Biological Processes, Diseases and Environmental Agents’ Risk. Third annual symposium of the Comparative Mouse Genomics Centers Consortium (CMGCC), Cell Cycle and DNA Repair Variants, June 1 to June 4, M. D. Anderson Cancer Center, Science Park - Research Division, Austin. Poster; Abstract.
Chen J, Gowrisankar S, Jegga AG, Livingston R, Niederhausern AV, Crawford DC, Carlson CS, Rieder MJ, Weiss RB, Nickerson DA and Aronow BJ 2004. PolyDoms: Web Resource for Initial Functional Characterization of Protein Polymorphisms. Third annual symposium of the Comparative Mouse Genomics Centers Consortium (CMGCC), Cell Cycle and DNA Repair Variants, June 1 to June 4, M. D. Anderson Cancer Center, Science Park - Research Division, Austin. Poster; Abstract.
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